机读格式显示(MARC)
- 000 03096cam a2200397 i 4500
- 008 190715s2019 ne a b 000 0 eng d
- 020 __ |a 9780128167595 (hbk.)
- 035 __ |a (OCoLC)1111660848
- 040 __ |a AU@ |b eng |c AU@ |e rda |d OCLCF |d OCLCO |d U3G |d SFB |d AS
- 050 _4 |a RC853 |b .D78 2019
- 099 __ |a CAL 022020030989
- 245 00 |a Drug-induced liver injury / |c edited by Anup Ramachandran, Hartmut Jaeschke.
- 264 _1 |a Amsterdam, The Netherlands : |b Elsevier Academic Press, |c 2019.
- 300 __ |a xv, 272 pages : |b illustrations (chiefly colour) ; |c 23 cm.
- 336 __ |a text |2 rdacontent
- 337 __ |a unmediated |2 rdamedia
- 338 __ |a volume |2 rdacarrier
- 490 1_ |a Advances in pharmacology ; |v 85
- 504 __ |a Includes bibliographical references.
- 505 0_ |a 1. Primary hepatocytes and their cultures for the testing of drug-induced liver injury / V?ia Vilas-Boas, Axelle Cooreman, Eva Gijbels, Raf Van Campenhout, Emma Gustafson, Steven Ballet, Pieter Annaert, Bruno Cogliati and Mathieu Vinken -- 2. Cell death in drug-induced liver injury / Andrea Iorga and Lily Dara -- 3. Drug-induced liver injury in obesity and nonalcoholic fatty liver disease / Julien Allard, Dounia Le Guillou, Karima Begriche and Bernard Fromenty -- 4. Role and mechanisms of autophagy in alcohol-induced liver injury / Xiaojuan Chao and Wen-Xing Ding -- 5. Mechanisms of idiosyncratic drug-induced liver injury / Jack Uetrecht -- 6. Idiosyncratic drug-induced liver injury in patients: detection, severity assessment, and regulatory implications / Paul B. Watkins -- 7. Acetaminophen hepatotoxicity: A mitochondrial perspective / Anup Ramachandran and Hartmut Jaeschke -- 8. Biomarkers of drug-induced liver injury / Mitchell R. McGill and Hartmut Jaeschke -- 9. Mechanisms and biomarkers of liver regeneration after drug-induced liver injury / Melissa M. Clemens, Mitchell R. McGill and Udayan Apte -- 10. Evaluation and treatment of acetaminophen toxicity / Erik S. Fisher and Steven C. Curry.
- 520 __ |a Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more.
- 650 _0 |a Liver |x Wounds and injuries.
- 650 _0 |a Drugs |x Side effects.
- 700 1_ |a Ramachandran, Anup, |e editor.
- 700 1_ |a Jaeschke, Hartmut, |e editor.
- 830 _0 |a Advances in pharmacology ; |v 85.