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• 008 180314s2018 sz a b 000 0 eng d

• 010 __ |a 2018934395

• 020 __ |a 9783319770956

• 020 __ |a 9783319770949 (print)

• 024 7_ |a 10.1007/978-3-319-77095-6 |2 doi

• 035 __ |a (WaSeSS)ssj0001986923

• 040 __ |a WaSeSS |b eng |e rda |c WaSeSS |d WaSeSS

• 050 _4 |a QD450-882

• 072 _7 |a PNR |2 bicssc

• 072 _7 |a SCI013050 |2 bisacsh

• 082 04 |a 541 |2 23

• 090 __ |a O62/O77

• 093 __ |a O62 |2 5

• 099 __ |a CAL 022018102364

• 100 1_ |a Ortega Arroyo, Jaime. |e author.

• 245 10 |a Investigation of nanoscopic dynamics and potentials by interferometric scattering microscopy / |c Jaime Ortega Arroyo.

• 264 _1 |a Cham : |b Springer, |c 2018.

• 300 __ |a xxxvi, 142 pages : |b illustrations ; |c 25 cm.

• 336 __ |a text |b txt |2 rdacontent

• 337 __ |a unmediated |b n |2 rdamedia

• 338 __ |a volume |b nc |2 rdacarrier

• 490 1_ |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5053

• 504 __ |a Includes bibliographical references.

• 505 0_ |a Introduction -- Non-fluorescent single-molecule approaches to optical microscopy -- Experimental Methods -- Anomalous diffusion due to interleaflet coupling and molecular pinning -- Structural dynamics of myiosin 5a -- All optical label-free detection, imaging and tracking of single proteins -- Single-molecule chemical dynamics: direct observation of physical autocatalysis -- Outlook.

• 520 __ |a This thesis offers a unique guide to the development and application of ultrasensitive optical microscopy based on light scattering. Divided into eight chapters, it covers an impressive range of scientific fields, from basic optical physics to molecular biology and synthetic organic chemistry. Especially the detailed information provided on how to design, build and implement an interferometric scattering microscope, as well as the descriptions of all instrumentation, hardware interfacing and image processing necessary to achieve the highest levels of performance, will be of interest to researchers now entering the field.

• 650 _0 |a Chemistry.

• 650 _0 |a Organic chemistry.

• 650 _0 |a Physical chemistry.

• 650 _0 |a Cell biology.

• 650 _0 |a Atoms.

• 650 _0 |a Physics.

• 830 _0 |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5053.

• 856 40 |z Pitt users please click through to access via SpringerLink ebooks - Chemistry and Materials Science (2018) |u http://pitt.idm.oclc.org/login?url=https://link.springer.com/openurl?genre=book&isbn=978-3-319-77094-9

• 920 __ |a 215010 |z 1

• 998 __ |a NMU