机读格式显示(MARC)
- 000 02768cam a2200373 i 4500
- 008 210202s2021 sz a b 001 0 eng d
- 020 __ |a 9783030638160 : |c CNY352.61
- 040 __ |a YDX |b eng |c YDX |e rda |d EBLCP |d UKBTH |d OCLCF |d GW5XE
- 100 1_ |a Joshi, Rucha |q (Rucha Vinay), |e author.
- 245 10 |a Collagen biografts for tunable drug delivery / |c Rucha Joshi.
- 264 _1 |a Cham, Switzerland : |b Springer, |c [2021]
- 300 __ |a xii, 107 pages : |b illustrations ; |c 24 cm.
- 336 __ |a text |b txt |2 rdacontent
- 337 __ |a unmediated |b n |2 rdamedia
- 338 __ |a volume |b nc |2 rdacarrier
- 490 1_ |a SpringerBriefs in applied sciences and technology
- 504 __ |a Includes bibliographical references and index.
- 505 0_ |a Introduction to drug delivery -- From in vivo synthesis to in vitro drug delivery device formation -- Creating tunable collagen matrices : an approach inspired by in-vivo collagen synthesis and self-assembly -- Collagen biografts for chronic wound healing -- Application of collagen fibril biografts for enhancing local vascularization in an in-vivo chick chorioallantoic membrane (CAM) model.
- 520 __ |a This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.
- 650 _0 |a Biomedical materials |x Therapeutic use.
- 650 _0 |a Collagen |x Therapeutic use.
- 650 _0 |a Drugs |x Controlled release.
- 650 _0 |a Tissue engineering.
- 650 _0 |a Biomedical engineering.
- 830 _0 |a SpringerBriefs in applied sciences and technology.