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MARC状态:审校  文献类型:西文图书 浏览次数:38 

题名/责任者:
Drug-induced liver injury / edited by Anup Ramachandran, Hartmut Jaeschke.
版本说明:
First edition.
出版发行项:
Amsterdam, The Netherlands : Elsevier Academic Press, 2019.
ISBN:
9780128167595 (hbk.)
ISBN:
0128167599
载体形态项:
xv, 272 pages : illustrations (chiefly colour) ; 23 cm.
丛编说明:
Advances in pharmacology ; 85
丛编统一题名:
Advances in pharmacology ; 85.
附加个人名称:
Ramachandran, Anup, editor.
附加个人名称:
Jaeschke, Hartmut, editor.
论题主题:
Liver-Wounds and injuries.
论题主题:
Drugs-Side effects.
中图法分类号:
R575
书目附注:
Includes bibliographical references.
内容附注:
1. Primary hepatocytes and their cultures for the testing of drug-induced liver injury / V?ia Vilas-Boas, Axelle Cooreman, Eva Gijbels, Raf Van Campenhout, Emma Gustafson, Steven Ballet, Pieter Annaert, Bruno Cogliati and Mathieu Vinken -- 2. Cell death in drug-induced liver injury / Andrea Iorga and Lily Dara -- 3. Drug-induced liver injury in obesity and nonalcoholic fatty liver disease / Julien Allard, Dounia Le Guillou, Karima Begriche and Bernard Fromenty -- 4. Role and mechanisms of autophagy in alcohol-induced liver injury / Xiaojuan Chao and Wen-Xing Ding -- 5. Mechanisms of idiosyncratic drug-induced liver injury / Jack Uetrecht -- 6. Idiosyncratic drug-induced liver injury in patients: detection, severity assessment, and regulatory implications / Paul B. Watkins -- 7. Acetaminophen hepatotoxicity: A mitochondrial perspective / Anup Ramachandran and Hartmut Jaeschke -- 8. Biomarkers of drug-induced liver injury / Mitchell R. McGill and Hartmut Jaeschke -- 9. Mechanisms and biomarkers of liver regeneration after drug-induced liver injury / Melissa M. Clemens, Mitchell R. McGill and Udayan Apte -- 10. Evaluation and treatment of acetaminophen toxicity / Erik S. Fisher and Steven C. Curry.
摘要附注:
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more.
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