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Online Public Access Catalogue

题名/责任者:

Improving the therapeutic ratio in head and neck cancer / Randall J. Kimple.

出版发行项:

San Diego : Academic Press is an Imprint of Elsevier, 2019.

ISBN:

9780128178683

载体形态项:

376 pages ; 25 cm.

丛编说明:

Cancer sensitizing agents for chemotherapy, 24683183 ; 6

附加个人名称:

Kimple, Randall J., editor.

论题主题:

Head-Cancer.

论题主题:

Neck-Cancer.

论题主题:

Head and Neck Neoplasms-therapy.

论题主题:

Head and Neck Neoplasms-pathology.

中图法分类号:

R739.91

内容附注:

v. 6. Improving the therapeutic ratio in head

摘要附注:

"Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites"--

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